منابع مشابه
Diversity of staphylococci exhibiting high-level resistance to mupirocin.
Plasmids mediating high-level resistance to mupirocin (MIC greater than 1000 mg/L) in staphylococci from various sources were studied by restriction endonuclease cleavage. Several patterns were obtained but six plasmids isolated from various Staphylococcus aureus and S. epidermidis strains were indistinguishable. The diversity and spread of these plasmids is illustrated.
متن کاملEmergence of high-level mupirocin resistance in coagulase-negative staphylococci associated with increased short-term mupirocin use.
In our hospital, mupirocin has increasingly been used for peri-operative decolonization of Staphylococcus aureus. The target for mupirocin is isoleucyl tRNA synthetase (ileS). High-level resistance to mupirocin is conferred by acquisition of plasmids expressing a distinct ileS gene (ileS2). Here we evaluated the longitudinal trends in high-level mupirocin resistance in coagulase-negative staphy...
متن کاملMupirocin resistance among staphylococci: trends in the southern region of Ireland.
Sir, Mupirocin is a topical antibiotic used particularly to eradicate methicillin-resistant Staphylococcus aureus (MRSA) carriage and to prevent infection. It is currently not mandatory in Ireland to screen patients for MRSA and decolonize them. Mupirocin-resistant strains are divided into two distinct groups: those with low-level mupirocin resistance (LMR); and those with high-level mupirocin ...
متن کاملClonal dissemination of mupirocin-resistant staphylococci in Greek hospitals.
OBJECTIVES To determine the rates of mupirocin resistance in staphylococci during a 4 year period (1999-2002) in Greece. MATERIALS A total of 1200 Staphylococcus aureus and 2760 coagulase-negative staphylococci (CoNS), consecutively collected from four Greek hospitals located in different geographical areas, were tested for susceptibility to mupirocin using the Etest and a reference agar dilu...
متن کاملPhenotypic and genotypic mupirocin resistance among Staphylococci causing prosthetic joint infection.
Mupirocin MICs and mupA presence were determined in 108 staphylococci causing prosthetic joint infection. Zero of 35 isolates (0%) of methicillin-susceptible Staphylococcus aureus, 4/15 (27%) methicillin-resistant S. aureus isolates, 3/16 (19%) methicillin-susceptible coagulase-negative staphylococci, and 11/42 (26%) methicillin-resistant coagulase-negative staphylococci were mupirocin resistan...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 1990
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/25.4.497